multidrug-resistant and extensively drug-resistant tuberculosis
نویسندگان
چکیده
multidrug-resistant (mdr) and extensively drug-resistant (xdr) tuberculosis (tb) are increasing globally. treatment options for these patients are very limited. although treatment of these patients with standardized regimen is associated with high mortality and morbidity, rational usage of new drugs might be promising. in this study we will review epidemiology of xdr-tb and tdr-tb in iran and the world.
منابع مشابه
Multidrug-resistant and extensively drug-resistant tuberculosis.
Tuberculosis (TB) can usually be treated with a course of four standard, or first-line, anti-TB drugs. If these are misused or mismanaged (that is, when drugs are taken in the wrong combination, are fewer than those prescribed, or are taken in insufficient doses or not at the proper time), multidrugresistant TB (MDR-TB) can develop. MDR-TB is a form of disease resistant to the most important an...
متن کاملMultidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis.
The continuing spread of drug-resistant tuberculosis (TB) is one of the most urgent and difficult challenges facing global TB control. Patients who are infected with strains resistant to isoniazid and rifampicin, called multidrug-resistant (MDR) TB, are practically incurable by standard first-line treatment. In 2012, there were approximately 450,000 new cases and 170,000 deaths because of MDR-T...
متن کاملMultidrug- and Extensively Drug-Resistant Tuberculosis, Germany
We evaluated risk factors and treatment outcomes associated with multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) in Germany in 2004-2006. In 177 (4%) of 4,557 culture-positive TB cases, Mycobacterium tuberculosis isolates were identified as MDR TB; an additional 7 (0.15%) met criteria for XDR TB. Of these 184 patients, 148 (80%) were born in countries of the for...
متن کاملMultidrug and extensively drug-resistant tuberculosis.
The emergence of drug-resistant tuberculosis (TB) compromises global tuberculosis control. The incidence of multidrug-resistant strains (MDR) defined as resistant to the two main antituberculosis drugs, rifampicin and isoniazid, was raised in the 1990s. Ten percent of these strains have developed additional resistance to the main second-line antituberculosis drugs: fluoroquinolones and aminogly...
متن کاملMultidrug-resistant and extensively drug resistant tuberculosis in Kashmir, India.
BACKGROUND To study the profile of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in tertiary care hospital setting, representing almost the whole affected population in Kashmir valley of India. METHODOLOGY A total of 910 cases of pulmonary tuberculosis were enrolled over four years. Among these, cases of MDR-TB and XDR-TB were meticulously stud...
متن کاملExtensively drug-resistant tuberculosis.
Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any fluoroquinolone, and at least one of three injectable second-line drugs (amikacin, capreomycin, or kanamycin). The definition has applicable clinical value and has allowed for more uniform surveillance in varied international settings...
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عنوان ژورنال:
archives of pediatric infectious diseasesجلد ۳، شماره ۱ TB، صفحات ۰-۰
کلمات کلیدی
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